IGF-1 LR3 1MG

Long Arg3 Insulin-like Growth Factor-1. An engineered, highly potent 83-amino acid analog of human IGF-1 featuring a substitution of Glutamic Acid for Arginine at position 3 and a 13-amino acid N-terminal extension. This structural configuration significantly downregulates its affinity for IGF-binding proteins (IGFBPs), dramatically extending its biological half-life and availability in cellular systems. It is widely researched for its role in stimulating muscle cell hyperplasia, accelerating protein synthesis, and activating the PI3K/Akt signaling pathway during tissue hypertrophy studies.